The Flowers of China-Pakistan Friendship are in Full Bloom in Lu Daopei Hospital

Lu Daopei Team Worked Seamlessly to Minimized Patient’s Misery

Maisha, a 4.5 years old girl comes from Pakistan. In September 2014, has the first symptoms "fever and cough". In Aga Khan University Hospital (Pakistan) hospital’s diagnosis was "acute B lymphoblastic leukemia". A course of "VP" chemotherapy was given, and the bone marrow morphology reexamination revealed a remission of the disease, and 8 courses of regular chemotherapy were followed, and the bone marrow morphology and immunity residue were not monitored during this period.

In May 2017, she had a fever again. 3.16% was malignant blasts B lymphocyte. The result of blood routine and bone marrow morphology in the local hospital showed a relapse of the disease.

On August 18, 2017, after the patient compared the BMT successful rate and expenditure of many medical centers globally, she came to our hospital for the first time for further treatment. Bone marrow biopsy test showed she is not in complete remission, it means her condition is not ready for blood and bone marrow transplantation.

After a multi-discipline consultation meeting, our hematologists suggest her to take part in the CAR-T clinical trial before BMT. Cause CAR-T have a big chance to make her into complete remission which is the best condition for BMT. In our 300 cases of CAR-T, the complete remission rate is about 90%.
On Sept. 1st CD19-CART cells infusion was done as cellular immune therapy, three reviews followed all showed that she got complete remission, and there were no malignant blasts cells were seen in the immune residual. This lays the foundation for the next step-Blood and Bone Marrow Transplantation.

The China Marrow Donor Program(CMDP) as First time Donated Hematopoietic Stem Cells to Pakistani Patient

The CMDP found an unrelated female donor whose HLA matching site is 10/10 with Maisha. On December 5, 2017 is a miracle date for Maisha. Allogeneic hematopoietic stem cell transplantation was carried on for her. Leucocyte graft survival at +15 days, platelet graft survival at +6 days. Appeared infectious diarrhea at -3 days, the stool returned to normal after positive local anti - inflammatory treatment. On December 22, she finally out of air laminar flow room. She is in disease free condition right now

Pakistani Embassy Deputy Came to Visit Maisha’s Family

Mr. Ahmad Bilal Malik, the Pakistani embassy deputy were invited by our international center to visit Maisha at the hospital. He went to Maisha’s room with gift and wish her could get well soon. “The environment, equipment and medical staffs of Lu Daopei hospital give me a very good impression. I can see humanitarian spirit everywhere in this hospital. I believe Maisha could get the best treatment and services here. More and more Pakistanis are coming to China to see doctors. As I know, they can get good care and treatment. Thanks to China for your help, thanks doctor, thanks Lu Daopei hospital!” said by Mr. Ahmad Bilal Malik.